Eric Dane dies at 53 after ALS diagnosis — Grey’s Anatomy and Euphoria star remembered
eric dane, the actor best known for his turns on a long-running medical drama and a hit teen series, has died aged 53, less than a year after revealing he had amyotrophic lateral sclerosis (ALS). His family announced he passed following a courageous battle with the disease; he spent his final months raising funds and awareness for the most common form of motor neurone disease.
Eric Dane: career highlights and defining roles
Eric Dane rose to prominence on the medical drama where he portrayed Dr Mark Sloan, often known by a memorable nickname tied to his character's allure. He first appeared in the show's second series and went from a single-episode guest arc to appearing in a further 138 episodes, later returning to the role as a main cast member. He was also widely recognised for playing Cal Jacobs on the teen drama that drew intense attention for its portrayal of youth culture.
His screen work extended beyond those two flagship roles. He made his television debut in the early 1990s on a coming-of-age series, and subsequently appeared in other drama series and several films. Notable credits in his filmography include appearances in family comedies and ensemble romantic features, as well as roles in genre and action projects. Another recurring television part saw him play a captain in an action drama series.
- Television breakout: guest appearance that expanded into a long-term role on a major medical drama.
- High-profile drama role: family patriarch on a prominent teen series.
- Film appearances: varied supporting roles in mainstream studio pictures.
Final months, family and advocacy
eric dane publicly shared his ALS diagnosis in April 2025 and devoted his remaining months to raising funds and awareness for motor neurone disease. His family said he spent his final days surrounded by close friends, his wife and his two daughters, who were described as the center of his world. They said he adored his fans and was grateful for the outpouring of support he received.
Representatives confirmed his death from ALS. The condition is one of the main forms of motor neurone disease, a progressive illness that affects movement and requires specialist care; there is no cure and treatment focuses on symptom management. In the period after his announcement, he was described as determined to make a difference for others facing the disease.
Plans for a memoir were noted as due for publication later this year. The book's release is expected to proceed as scheduled, with details to be confirmed.
Tributes and legacy
Colleagues and collaborators led a wave of tribute messages, highlighting both his professional talent and his personal warmth. A long-time co-star from the medical drama remembered him as a joy to work with and praised his comic timing and intelligence. Other castmates reflected on his ability to bring levity to set and to deliver emotionally resonant performances. The creator of the teen drama expressed grief at the loss and called working with him an honor.
Beyond on-screen fame, his final months reframed his public legacy around advocacy and awareness for ALS. He channeled his platform into fundraising and education efforts, seeking to draw attention to a condition that shortens lives and demands ongoing care from multidisciplinary teams.
The suddenness of his decline and his choice to go public with his diagnosis brought renewed focus on motor neurone disease in the entertainment community and among fans. He leaves behind his wife and two daughters, and a body of work that spans television and film. His family and peers said he will be deeply missed and lovingly remembered.
Recent statements indicate details surrounding memorial arrangements and the memoir timeline may evolve; further updates are expected as the family shares additional information.
