Memory of a Killer: Patrick Dempsey’s new crime thriller, full cast, episode count, release schedule, and where to watch in the U.S.

Patrick Dempsey has officially stepped back into weekly television with Memory of a Killer, a new crime drama built around a high-concept collision of family life, professional violence, and failing memory. The series launched with a two-night premiere event on Sunday, January 25, 2026 (scheduled for roughly 10:00 p.m. ET, following live sports) and Monday, January 26, 2026 at 9:00 p.m. ET, before settling into a regular Monday night slot.

For viewers searching “new Patrick Dempsey show” after years of associating him with Grey’s Anatomy, this project is a deliberate pivot: he plays a man who looks like a normal suburban dad but secretly works as a contract killer—while showing signs of early-onset Alzheimer’s that threaten to unravel both lives.

What is Memory of a Killer about?

Dempsey stars as Angelo Doyle, a husband and father who presents as an ordinary family man. Behind the scenes, Angelo is a hired assassin with a long, dangerous history—and the show’s central tension comes from his memory beginning to slip at the worst possible time.

That deterioration isn’t just a personal crisis; it’s a plot engine. A hitman’s safety depends on precision: names, routes, rules, alliances. When those details fade, every relationship becomes a liability, and every “routine” job becomes unpredictable. The show uses that pressure to force Angelo’s home life and criminal life into the same frame, raising the stakes for everyone around him.

If you’ve seen people type “memories of a killer,” note the title is Memory of a Killer (singular). It’s also separate from older similarly titled films; this is a new U.S. series with its own continuity.

Memory of a Killer cast: Patrick Dempsey and the main ensemble

Here’s the core cast you’ll see most often in Season 1:

• Patrick Dempsey as Angelo Doyle

• Michael Imperioli as Dutch

• Richard Harmon as Joe (Angelo’s right-hand man)

• Odeya Rush as Maria (Angelo’s pregnant daughter)

• Daniel David Stewart as Jeff (Maria’s husband)

• Peter Gadiot as Dave

Recurring players being highlighted early include:

• Gina Torres as Linda Grant

• Michaela McManus as Nicky

The lineup signals what the series wants to be: prestige-leaning crime drama with recognizable faces, but structured for weekly cliffhangers and a steady Monday-night audience.

Memory of a Killer episodes: how many, and what’s the release schedule?

Season 1 is set to run 10 episodes.

Known early schedule and titles (all times ET):

• Episode 1, “Pilot” — aired Sunday, January 25, 2026 (scheduled after live sports; timing can slide)

• Episode 2, “Ferryman” — aired Monday, January 26, 2026 at 9:00 p.m. ET

• Episode 3, “Samurai” — scheduled Monday, February 2, 2026 at 9:00 p.m. ET

After the premiere event, the working expectation is one new episode each Monday at 9:00 p.m. ET, unless the broadcaster shifts it for special programming.

Memory of a Killer: where to watch (and how to watch the broadcast)

If you’re trying to “watch live” in the U.S., here are the practical options:

• Live on broadcast TV: Tune to your local affiliate of the U.S. broadcast network airing the show on Mondays at 9:00 p.m. ET. An antenna often works in many areas, and cable or satellite subscriptions typically carry local affiliates.

• Next-day streaming: Episodes are also available the next day on the show’s primary on-demand streaming partner (subscription required in most cases).

• Live TV streaming bundles / on-demand purchase: Some paid TV bundles that include local broadcast affiliates may carry it live, and some digital storefronts may offer episodes for purchase after airing, depending on region.

If you’re specifically searching “watch …” plus the broadcaster’s name, the most reliable approach is still: local affiliate at airtime, then next-day on-demand.

Behind the headline: why Dempsey is back on weekly TV, and why this premise keeps getting greenlit

Dempsey’s return isn’t just nostalgia casting for Grey’s Anatomy fans. A 10-episode season lowers the barrier for actors who don’t want the grind of traditional long-network runs. It also fits how audiences watch now: shorter seasons, cleaner arcs, fewer filler weeks.

The premise—dangerous job plus cognitive decline—works because it creates built-in escalation without needing constant new villains. Every episode can raise tension simply by making Angelo less certain of what’s real, what’s remembered, and who he can trust. That also spreads stakes across stakeholders:

• Angelo’s family risks becoming collateral damage.

• Criminal associates face exposure if Angelo forgets rules, names, or secrets.

• Law enforcement and adversaries gain advantage as predictability collapses.

• The broadcaster and producers get a hook that’s easy to explain in one sentence, which matters in a crowded TV market.

What we still don’t know, and what to watch next

Early episodes set the chessboard, but several season-defining questions are still intentionally unanswered:

• How far along is Angelo’s condition right now, and how quickly will it progress?

• Is someone exploiting his decline, or is the danger purely the consequence of his double life?

• Which relationships are real—and which are transactional arrangements that will break the moment he slips?

Next steps are likely to fall into a few realistic lanes:

• A midseason point where Angelo’s memory failure causes a public mistake (trigger: an operation gone wrong)

• A family storyline turning from suspicion into discovery (trigger: repeated inconsistencies at home)

• A power struggle around Dutch and Joe as trust erodes (trigger: a missing detail with deadly consequences)

• A late-season sprint to “finish the job” before Angelo can’t (trigger: a clear medical turning point)

For viewers, the appeal is the same reason the search terms are spiking: Memory of a Killer asks a simple question and forces it to get messier every week—what happens when the most dangerous man in the room can’t trust his own mind?