Memory of a Killer: Patrick Dempsey’s new Fox show, cast, episodes, where to watch

Memory of a Killer is the latest Patrick Dempsey drama to hit broadcast TV, positioning the former Grey’s Anatomy star in a darker, action-first role: a suburban dad with a hidden life as a contract killer whose control starts slipping as memory loss sets in. The series launched with a two-night premiere event on Sunday, Jan. 25, 2026 (ET) and Monday, Jan. 26, 2026 (ET), and it now moves into its regular weekly slot on FOX.

If you’re searching “patrick dempsey new show,” “new patrick dempsey show,” or even the mis-typed “memories of a killer,” this is the one that’s trending — and the viewing options are straightforward once you know the schedule.

What the new series is about

Dempsey plays Angelo Doyle, a seemingly ordinary family man who has quietly been living a second life as a professional hitman. That double-life premise gets an extra pressure point: Angelo begins experiencing worsening memory problems tied to early-onset Alzheimer’s, forcing him to navigate jobs, family obligations, and law-enforcement scrutiny while losing confidence in what he remembers — and what he might forget at the worst possible moment.

The show is adapted from the Belgian story that inspired The Alzheimer Case (also known as De Zaak Alzheimer), with the TV version leaning into a U.S. crime-thriller pace: urgent jobs, close calls, and escalating consequences when Angelo’s mental “gaps” collide with a world that punishes mistakes.

Memory of a Killer cast and the Grey’s Anatomy connection

People looking up “memory of a killer cast” will find a lineup built around recognizable faces from prestige TV and crime dramas. Alongside Patrick Dempsey, the core ensemble includes:

• Michael Imperioli as Dutch, a key underworld figure in Angelo’s orbit

• Gina Torres as FBI Agent Linda Grant

• Odeya Rush as Maria, Angelo’s daughter

• Richard Harmon as Joe, Angelo’s close associate

• Daniel David Stewart as Jeff, Maria’s husband

• Peter Gadiot as Dave

For longtime network-TV viewers, Dempsey’s return is also a tonal pivot from Grey’s Anatomy. Fans who remember “McDreamy” may be surprised by how far this character sits from Derek Shepherd: less romance, more menace, and a constant sense that one mistake could destroy both of Angelo’s lives.

Memory of a Killer episodes and schedule

Season 1 is set at 10 episodes, with FOX positioning the rollout as an early-year thriller anchor. The series began with a two-night kickoff and then settles into a weekly cadence.

(Entries labeled approx. reflect the expected weekly pattern after the confirmed early schedule.)

Memory of a Killer where to watch — FOX, Hulu, and “watch fox” options

For anyone typing “memory of a killer where to watch,” the primary answer in the U.S. is simple: watch it live on FOX at its scheduled airtime, then stream the following day on Hulu.

There are also official FOX app-based options depending on your provider and device setup. If you’re searching “watch fox” because you want a live stream, the practical path is typically either (1) FOX through your live TV provider on supported devices, or (2) catching up next-day on Hulu if you don’t need it live.

Availability outside the U.S. can vary by region and licensing; if a platform isn’t listed for your market, it may be unavailable at launch or arrive later.

What’s next for Patrick Dempsey on TV

In the near term, the focus is on whether Memory of a Killer can sustain momentum beyond the hook of its premise. FOX’s rollout suggests the network sees this as more than a limited stunt: a full 10-episode season with a stable time slot is a vote of confidence.

For Dempsey, it’s also a clean repositioning: a lead role built around tension and vulnerability rather than the comfort-TV charisma of his Grey’s Anatomy era. If the series holds its audience through February and March, it could become the defining “new Patrick Dempsey show” of the 2026 winter TV slate — especially for viewers who want a weekly thriller rather than a binge-only drop.

Sources consulted: FOXFLASH; People; TV Guide; Hulu; IMDb; The Futon Critic