What to know about Floyd Mayweather-Manny Pacquiao rematch: Sept. 19 at the Sphere, odds and build-up

Manny Pacquiao is headed back into the ring opposite Floyd Mayweather Jr. for a rematch set for Saturday, Sept. 19 at the Sphere in Las Vegas, a development that closes a chapter that began with their first meeting in 2015. The fight will be broadcast on a streaming service.

Rematch set for Sept. 19 at the Sphere in Las Vegas

Promoters have scheduled the rematch for Saturday, Sept. 19 at the Sphere in Las Vegas. The event will be presented on a streaming platform. It arrives more than a decade after the pair first met in 2015.

Mayweather opens as favorite; betting markets shift

Bookmakers opened the rematch with Floyd Mayweather Jr. as the favorite. Initial market lines showed Mayweather at -175 and Manny Pacquiao at +125. By Tuesday afternoon the market had moved, with Mayweather listed at -190 (an implied probability of 65. 5%) and Pacquiao at +140. These moves reflect early bettor sentiment and market adjustments in the days after the announcement.

How the 2015 fight and its legacy shape expectations

Their first meeting in 2015 ended with Mayweather emerging victorious by an easy unanimous decision. That fight set a record with 4. 6 million pay-per-view buys, though it was widely viewed as disappointing from an entertainment standpoint. That combination of commercial success and muted in-ring drama is central to how fans and bettors are approaching the rematch.

Manny Pacquiao: recent activity and comeback status

Manny Pacquiao had retired in 2021 before returning to competition and posting a draw against Mario Barrios last July. He is 47 years old. The comeback and that result are part of the public picture around his readiness for another high-profile matchup with Mayweather.

Floyd Mayweather Jr.: retirement, comebacks and exhibition plans

Floyd Mayweather Jr. retired in 2015 after a win against Andre Berto, then returned in August 2017 to fight Conor McGregor. He is currently 49 years old. Both fighters also have exhibition matches planned this year: Pacquiao is scheduled to face Ruslan Provodnikov on April 18, while Mayweather appears to be heading toward an April 25 exhibition against Mike Tyson.

What to watch next and what’s uncertain

Key items to monitor as the fight approaches include final confirmation of undercard plans, promotional buildup, and whether public interest will mirror—or eclipse—the enormous pay-per-view numbers from 2015. Market odds are likely to continue shifting as additional details emerge and as both fighters complete their exhibition dates. Details may evolve in the coming weeks; any developing information should be treated as provisional.

In short: a rematch that reawakens a high-profile pairing is now scheduled for Sept. 19 at the Sphere in Las Vegas, with Floyd Mayweather Jr. opening as a betting favorite in early markets and Manny Pacquiao positioned as the underdog amid a recent return to action.