Louisville’s 2026 Football Slate: Ole Miss Opener, Friday Nights, FSU Matchup
The University of Louisville has revealed an exciting football slate for the 2026 season, featuring a mix of challenging opponents and key matchups. Under the leadership of head coach Jeff Brohm, the Cardinals’ season opener is set against Ole Miss in Nashville, TN, during Labor Day weekend. This matchup is particularly notable as it marks the second time these teams will face each other, following a previous meeting in 2021.
Key Highlights of Louisville’s 2026 Football Schedule
The Cardinals’ 2026 schedule includes a total of six home games, five away games, and one neutral-site contest. Furthermore, fans can expect a Friday night game or two throughout the season. The schedule features dynamic clashes with national powerhouse teams and rivals.
- Opening Game: September 5 or 6 – vs. Ole Miss (Nashville, TN)
- Friday Night Home Opener: September 11 – vs. Villanova
- First Meeting: September 19 – vs. SMU
- Traditional Rivalry Finale: November 28 – at Kentucky
September matchups
- Sept 5/6 – vs. Ole Miss: A significant opener against a team that recently competed in the College Football Playoff.
- Sept 11 – vs. Villanova: First-ever meeting with FCS semifinalists of 2025.
- Sept 19 – vs. SMU: The Mustangs have historically led the series.
- Sept 26 – vs. Wake Forest: A rematch of a prior win for Louisville in 2022.
October to November Overview
This stretch includes strenuous challenges against top-tier opponents. Notable games include:
- October 3 – at NC State: Historically, Louisville has the upper hand.
- October 9 – vs. Florida State: A crucial Friday night showdown and a long-standing rivalry.
- October 31 – vs. Stanford: A rematch of an exciting game from 2024.
- November 21 – vs. Pittsburgh: Final ACC game with a balanced history.
- November 28 – at Kentucky: The annual rivalry returns during Thanksgiving weekend.
Coach Jeff Brohm’s Leadership
Following two successful seasons, Coach Brohm has an impressive record of 28-12. His efforts to refresh the team include the addition of 30 transfers and 20 high school recruits. The Cardinals hope to build on their previous seasons, which included strong performances, such as a 41-0 victory against Kentucky and a win in the Boca Raton Bowl.
Looking ahead to the 2026 season, Louisville’s fans can anticipate a thrilling year filled with fierce competition. As the Cardinals face off against both familiar rivals and new challenges, the upcoming lineup promises to be an exhilarating experience for football supporters across the region.